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Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp

Human Reproduction · 2013 · Vol. 28(3) · pp. 777–784
Nigel K. SteptoSamantha CassarAnju E. JohamStephen HutchisonCheryce L. HarrisonRebecca F. GoldsteinHelena Teede

Abstract

This investigator-initiated trial was supported by grants from the National Health & Medical Research Council (NHMRC) Grant number 606553 (H.J.T., N.K.S. and S.K.H.) as well as Monash University and The Jean Hailes Foundation. H.J.T. is an NHMRC Research Fellow. N.K.S. is supported through the Australian Government's Collaborative Research Networks (CRN) programme. A.E.J. is a Jean Hailes and NHMRC scholarship holder. The authors declare that there is no conflict of interest associated with this manuscript.

Ovarian function and disordersReproductive Biology and FertilityLipid metabolism and disordersPolycystic ovaryInsulin resistanceMedicineEndocrinologyInternal medicineClampOvaryInsulinGynecology

MeSH terms

Academic Medical CentersAdultCross-Sectional StudiesFemaleFollicular PhaseHumansInsulin ResistanceObesityOutpatient Clinics, HospitalPolycystic Ovary SyndromePrediabetic StateVictoriaGlucose Clamp TechniqueCohort StudiesBody Mass Index

Funding

  • Australian Government
  • Monash University
  • Medical Research Council
  • National Health and Medical Research Council
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