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Biological Activities of Hydrazone Derivatives

Molecules · 2007 · Vol. 12(8) · pp. 1910–1939
Sevım RollasŞ. Güniz Küçükgüzel

Abstract

There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, antimalarial, antimicrobial, antimycobacterial, antitumoral, vasodilator, antiviral and antischistosomiasis activities. Hydrazones possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazones that possess varied biological activities.

Synthesis and biological activitySynthesis of heterocyclic compoundsSynthesis and Characterization of Heterocyclic CompoundsAntimycobacterialChemistryHydrazoneBiological activityAntimicrobialPharmacologyCombinatorial chemistryStereochemistryBiochemistryOrganic chemistry

MeSH terms

AnimalsHumansHydrazones
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