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Adipose-Derived Stem Cells for Regenerative Medicine

Circulation Research · 2007 · Vol. 100(9) · pp. 1249–1260
Jeffrey M. GimbleAdam J. KatzBruce A. Bunnell

Abstract

The emerging field of regenerative medicine will require a reliable source of stem cells in addition to biomaterial scaffolds and cytokine growth factors. Adipose tissue represents an abundant and accessible source of adult stem cells with the ability to differentiate along multiple lineage pathways. The isolation, characterization, and preclinical and clinical application of adipose-derived stem cells (ASCs) are reviewed in this article.

Mesenchymal stem cell researchTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsAdipose tissueRegenerative medicineStem cellAdult stem cellCell biologyTissue engineeringBiologyMedicineImmunologyBiomedical engineering

MeSH terms

Adipose TissueCell DifferentiationCell SeparationHumansLipomaLiposarcomaTerminology as TopicObesityImmunophenotypingCell LineageProteomeTissue EngineeringCell ProliferationAdipogenesisAdult Stem Cells

Funding

  • Louisiana Gene Therapy Research Consortium
  • Pennington Biomedical Research Foundation
  • Tulane University
  • National Institutes of Health
  • National Center for Research Resources
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