article Open AccessTop 10% cited
The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster
Journal of Theoretical Biology · 2003 · Vol. 223(1) · pp. 1–18
Réka Albert✉(University of Minnesota)Hans G. Othmer(University of Minnesota)
Genomics and Chromatin DynamicsDevelopmental Biology and Gene RegulationRNA Research and SplicingDrosophila melanogasterGeneTopology (electrical circuits)Gene regulatory networkBiologyPolarity (international relations)Gene expressionExpression (computer science)GeneticsNetwork topology
MeSH terms
AnimalsBlood ProteinsCleavage Stage, OvumComplement C4Computer SimulationDrosophila melanogasterGenes, RegulatorMembrane ProteinsModels, GeneticProto-Oncogene ProteinsReceptors, Cell SurfaceGene ExpressionGenes, InsectDrosophila ProteinsWnt1 Protein
Citations
960
FWCI
9.34
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References
58
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99%
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References
Metabolic stability and epigenesis in randomly constructed genetic nets
Journal of Theoretical Biology · 1969 · 4,813 citations
Wnt signaling: a common theme in animal development
Genes & Development · 1997 · 2,571 citations
Boolean formalization of genetic control circuits
Journal of Theoretical Biology · 1973 · 957 citations
Hedgehog signaling in animal development: paradigms and principles
Genes & Development · 2001 · 2,990 citations
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