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A Length Polymorphism in the Circadian Clock Gene Per3 is Linked to Delayed Sleep Phase Syndrome and Extreme Diurnal Preference

SLEEP · 2003 · Vol. 26(4) · pp. 413–415
Simon ArcherDonna L. RobilliardDebra J. SkeneMarcel G. SmitsAdrian WilliamsJoséphine ArendtMalcolm von Schantz

Abstract

The length of the Per3 repeat region identifies a potential genetic marker for extreme diurnal preference.

Circadian rhythm and melatoninSleep and related disordersPsychological and Temporal Perspectives ResearchCircadian rhythmDelayed sleep phaseAllelePolymorphism (computer science)EndocrinologyInternal medicineAllele frequencyGeneticsBiologyMedicine

MeSH terms

AdolescentAdultChoice BehaviorCircadian RhythmFemaleGene FrequencyGenotypeHumansMaleNuclear ProteinsPolymorphism, GeneticSurveys and QuestionnairesTranscription FactorsSleep Disorders, Circadian RhythmPeriod Circadian Proteins
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