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Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model

Bone · 2008 · Vol. 43(5) · pp. 931–940
Zarana S. PatelSimon YoungYasuhiko TabataJohn A. JansenMark E. WongAntonios G. Mikos
Bone Tissue Engineering MaterialsPeriodontal Regeneration and TreatmentsSpine and Intervertebral Disc PathologyScaffoldChemistryVascular endothelial growth factorBone morphogenetic protein 2Bone morphogenetic proteinOsteoidBiomedical engineeringRegeneration (biology)Growth factorX-ray microtomography

MeSH terms

AnimalsGelatinMaleParticle SizeRats, Inbred F344RegenerationSkullTomography, X-Ray ComputedDrug Delivery SystemsNeovascularization, PhysiologicImplants, ExperimentalVascular Endothelial Growth Factor ARatsTissue ScaffoldsBone Morphogenetic Protein 2

Funding

  • National Science Foundation
  • Oral and Maxillofacial Surgery Foundation
  • National Institutes of Health
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Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model · Scinovex