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Influence of race/ethnicity on response to lupus nephritis treatment: the ALMS study

Lara D. Veeken · 2009 · Vol. 49(1) · pp. 128–140
David IsenbergGerald B. AppelGabriel ContrerasMary Anne DooleyEllen M. GinzlerDavid JayneJorge Sánchez‐GuerreroDavid WofsyXueqing YuNeil Solomons

Abstract

MMF and IVC have similar efficacy overall to short-term induction therapy for LN. However, race, ethnicity and geographical region may affect treatment response; more Black and Hispanic patients responded to MMF than IVC. As these factors are inter-related, it is difficult to draw firm conclusions about their importance.

Systemic Lupus Erythematosus ResearchRenal Diseases and GlomerulopathiesInflammatory Bowel DiseaseMedicineLupus nephritisInternal medicinePrednisoneClinical endpointRenal functionAdverse effectGastroenterologySystemic lupus erythematosusRandomized controlled trial

MeSH terms

AdolescentAdultAgedChildCyclophosphamideDrug Administration ScheduleDrug Therapy, CombinationHumansImmunosuppressive AgentsLupus NephritisMiddle AgedMycophenolic AcidOpportunistic InfectionsPrednisoneProspective Studies

Funding

  • Amgen
  • Bristol-Myers Squibb
  • F. Hoffmann-La Roche
  • Vifor Pharma
  • Genentech
Citations
352
FWCI
16.05
field-weighted impact
References
41
Percentile
100%
vs. same field & year
Citations per year
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