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Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue

Clinical Cancer Research · 2008 · Vol. 14(9) · pp. 2588–2592
Thian‐Sze WongXiaobing LiuBirgitta Yee‐Hang WongRaymond W. M. NgAnthony P.W. YuenWI Wei

Abstract

Overexpression of miR-184 might play an oncogenic role in the antiapoptotic and proliferative processes of tongue SCC. In addition, plasma miR-184 levels were associated with the presence of primary tumor. Further studies on the aberrantly expressed miRNAs in tongue SCC as well as using plasma miRNAs as novel tumor markers are warranted.

MicroRNA in disease regulationCancer-related molecular mechanisms researchCircular RNAs in diseasesmicroRNATongueBiologyCancer researchCell cultureCell growthCellBasal cellReal-time polymerase chain reactionMolecular biology

MeSH terms

Carcinoma, Squamous CellHumansTongueTongue NeoplasmsDown-RegulationUp-RegulationProto-Oncogene Proteins c-mycMicroRNAsCell Line, Tumor
Citations
766
FWCI
22.98
field-weighted impact
References
14
Percentile
100%
vs. same field & year
Citations per year
References
MicroRNA signatures in human cancers
Nature reviews. Cancer · 2006 · 7,589 citations
miR-21-mediated tumor growth
Oncogene · 2006 · 1,594 citations
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Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue · Scinovex