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Reduction of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With Raloxifene<SUBTITLE>Results From a 3-Year Randomized Clinical Trial</SUBTITLE>
JAMA · 1999 · Vol. 282(7) · pp. 637–637
Bruce Ettinger✉(Kaiser Permanente)
Abstract
In postmenopausal women with osteoporosis, raloxifene increases bone mineral density in the spine and femoral neck and reduces risk of vertebral fracture.
Bone health and osteoporosis researchEstrogen and related hormone effectsBone Metabolism and DiseasesMedicineRaloxifeneOsteoporosisSelective estrogen receptor modulatorPlaceboRandomized controlled trialAdverse effectInternal medicineStrontium ranelateTamoxifen
MeSH terms
AdultAgedEstrogensFemaleHumansMiddle AgedPiperidinesRadiographyRiskBone DensityOsteoporosis, PostmenopausalSpinal FracturesRaloxifene Hydrochloride
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References
Markers of bone resorption predict hip fracture in elderly women: The EPIDOS prospective study
Journal of Bone and Mineral Research · 1996 · 1,002 citations
Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis
Journal of Bone and Mineral Research · 1996 · 638 citations
Transection of the oesophagus for bleeding oesophageal varices
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