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Stochasticity in Transcriptional Regulation: Origins, Consequences, and Mathematical Representations

Biophysical Journal · 2001 · Vol. 81(6) · pp. 3116–3136

Thomas B. Kepler✉(Santa Fe Institute)Timothy C. Elston(North Carolina State University)

Gene Regulatory Network Analysis Evolution and Genetic Dynamics Mathematical Biology Tumor GrowthBistabilityStochastic processOperator (biology)Statistical physicsGeneralizationMaster equationSimple (philosophy)Stochastic modellingComputer scienceMathematical and theoretical biology

MeSH terms

Gene Expression RegulationModels, TheoreticalMonte Carlo MethodPromoter Regions, GeneticStochastic ProcessesTime FactorsTranscription, GeneticFeedback, Physiological

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Stochasticity in gene expression: from theories to phenotypes