reviewTop 1% cited
A Review of the Clinical, Economic, and Societal Burden of Treatment-Resistant Depression: 1996–2013
Psychiatric Services · 2014 · Vol. 65(8) · pp. 977–987
Abstract
Treatment-resistant depression exacts a substantial toll on patients' quality of life. At current rates of 12%-20% among all depressed patients, treatment-resistant depression may present an annual added societal cost of $29-$48 billion, pushing up the total societal costs of major depression by as much as $106-$118 billion. These findings underscore the need for research on the mechanisms of depression, new therapeutic targets, existing and new treatment combinations, and tests to improve the efficacy of and adherence to treatments for treatment-resistant depression.
Treatment of Major DepressionBipolar Disorder and TreatmentAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesDepression (economics)MedicineTreatment-resistant depressionQuality of life (healthcare)PsychiatryClinical trialSuicide preventionPoison controlMajor depressive disorderEmergency medicine
MeSH terms
Depressive Disorder, MajorMajor Depressive DisorderHumansQuality of LifeCost of IllnessDepressive Disorder, Treatment-Resistant
Citations
576
FWCI
21.03
field-weighted impact
References
82
Percentile
100%
vs. same field & year
Citations per year
Cited by
Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005–2017.
Journal of Abnormal Psychology · 2019 · 1,401 citations
References
Disparity in Depression Treatment Among Racial and Ethnic Minority Populations in the United States
Psychiatric Services · 2008 · 737 citations
Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression
Biological Psychiatry · 2008 · 893 citations
Clinical implications of Brief Psychiatric Rating Scale scores
The British Journal of Psychiatry · 2005 · 886 citations
Childhood and Adolescent Depression: A Review of the Past 10 Years. Part I
Journal of the American Academy of Child & Adolescent Psychiatry · 1996 · 2,098 citations
Nucleus Accumbens Deep Brain Stimulation Decreases Ratings of Depression and Anxiety in Treatment-Resistant Depression
Biological Psychiatry · 2009 · 861 citations
Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression
Biological Psychiatry · 2008 · 1,009 citations
Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D: Implications for Clinical Practice
American Journal of Psychiatry · 2006 · 3,835 citations
Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States
Archives of General Psychiatry · 1994 · 12,511 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.