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Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life

Thorax · 2010 · Vol. 65(12) · pp. 1045–1052

Nele Sigurs✉(University of Borås)Fatma Aljassim(Drottning Silvias barn- och ungdomssjukhus)Bengt Kjellman(Skaraborg Hospital)Paul D. Robinson(Children's Hospital at Westmead)F. Sigurbergsson(Reykjavík University)Ragnar Bjarnason(University of Iceland)Per Gustafsson(Drottning Silvias barn- och ungdomssjukhus)

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Abstract

Severe early RSV bronchiolitis is associated with an increased prevalence of allergic asthma persisting into early adulthood. Small airway dysfunction (LCI) is related to current asthma and airway inflammation but not to RSV bronchiolitis. Reduced spirometry after RSV may reflect airway remodelling.

Respiratory viral infections research Asthma and respiratory diseases Neonatal Respiratory Health ResearchMedicineWheezeAsthmaSpirometryBronchiolitisAllergyExhaled nitric oxideImmunologyCohortInternal medicine

MeSH terms

AsthmaBronchiolitis, ViralEpidemiologic MethodsFemaleHospitalizationHumansHypersensitivityInfantInfant, NewbornMalePulmonary VentilationRespiratory SoundsSkin TestsVital CapacityRespiratory Syncytial Virus Infections

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696

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23.72

field-weighted impact

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100%

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