review Open AccessTop 1% cited
Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis
BMJ · 2003 · Vol. 326(7404) · pp. 1423–1423
M R Law✉(Queen Mary University of London)N J Wald(Queen Mary University of London)A R Rudnicka(Queen Mary University of London)
Abstract
Statins can lower LDL cholesterol concentration by an average of 1.8 mmol/l which reduces the risk of IHD events by about 60% and stroke by 17%.
Lipoproteins and Cardiovascular HealthAntiplatelet Therapy and Cardiovascular DiseasesCoronary Interventions and DiagnosticsRosuvastatinPravastatinMedicineAtorvastatinSimvastatinInternal medicineFluvastatinStatinCholesterolLovastatin
MeSH terms
Double-Blind MethodHumansCholesterol, LDLRisk FactorsCohort StudiesRandomized Controlled Trials as TopicMyocardial IschemiaHydroxymethylglutaryl-CoA Reductase InhibitorsStroke
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1,733
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References
Comparative Dose Efficacy Study of Atorvastatin Versus Simvastatin, Pravastatin, Lovastatin, and Fluvastatin in Patients With Hypercholesterolemia (The CURVES Study) fn1fn1This study was supported by Parke-Davis, Division of Warner Lambert Company, Morris Plains, New Jersey. Manuscript received August 20, 1997; revised manuscript received and accepted November 24, 1997.
The American Journal of Cardiology · 1998 · 1,074 citations
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