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The Role of Growth Factors in Cartilage Repair

Clinical Orthopaedics and Related Research · 2011 · Vol. 469(10) · pp. 2706–2715

Lisa A. Fortier✉(Cornell University)Joseph U. BarkerEric J. StraussTaralyn M. McCarrel(Cornell University)Brian J. Cole

Abstract

The application of growth factors in the treatment of local cartilage defects as well as osteoarthritis appears promising; however, further research is needed at both the basic science and clinical levels before routine application.

Osteoarthritis Treatment and Mechanisms Periodontal Regeneration and Treatments Knee injuries and reconstruction techniquesMedicineCartilageAnatomy

MeSH terms

AnimalsCartilage DiseasesCartilage, ArticularDrug Therapy, CombinationFibroblast Growth FactorsHumansInsulin-Like Growth Factor IPlatelet-Derived Growth FactorRegenerationTransforming Growth FactorsBone Morphogenetic ProteinsChondrogenesisIntercellular Signaling Peptides and Proteins

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Efficacy and safety of platelet rich plasma in primary osteoarthritis of the knee joint