articleTop 10% cited
Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction
Bioorganic & Medicinal Chemistry Letters · 1996 · Vol. 6(15) · pp. 1819–1824
N.K. Terrett✉(Pfizer (United Kingdom))Andrew Bell(Pfizer (United Kingdom))David Brown(Pfizer (United Kingdom))Peter Ellis(Pfizer (United Kingdom))
Sexual function and dysfunction studiesHormonal and reproductive studiesPharmacological Effects and Toxicity StudiesSildenafilErectile dysfunctioncGMP-specific phosphodiesterase type 5PhosphodiesteraseChemistryPharmacologyEnzyme inhibitorPhosphodiesterase inhibitorTadalafilInternal medicine
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References
Multiple cyclic nucleotide phosphodiesterases.
Molecular Pharmacology · 1994 · 477 citations
Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors
Trends in Pharmacological Sciences · 1990 · 850 citations
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