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Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001–2006: Overview of the Transplant‐Associated Infection Surveillance Network (TRANSNET) Database

Clinical Infectious Diseases · 2010 · Vol. 50(8) · pp. 1091–1100

Dimitrios P. Kontoyiannis✉(The University of Texas MD Anderson Cancer Center)Kieren A. Marr(Fred Hutch Cancer Center)Benjamin J. ParkBarbara D. Alexander(Duke Medical Center)Elias Anaissie(University of Arkansas for Medical Sciences)Thomas J. Walsh(National Institutes of Health)James I. Ito(City Of Hope National Medical Center)David R. Andes(University of Wisconsin–Madison)John W. Baddley(University of Alabama at Birmingham)Janice M. Brown(Stanford Medicine)Lisa Brumble(Jacksonville College)Alison G. Freifeld(University of Nebraska Medical Center)Susan Hadley(Tufts Medical Center)Loreen A. Herwaldt(University of Iowa)Carol A. Kauffman(VA Ann Arbor Healthcare System)Katherine M. Knapp(St. Jude Children's Research Hospital)G. Marshall Lyon(Emory University)Vicki A. Morrison(University of Minnesota Medical Center)Genovefa A. Papanicolaou(Memorial Sloan Kettering Cancer Center)Thomas F. Patterson(The University of Texas Health Science Center at San Antonio)Trish M. Perl(Johns Hopkins University)Mindy G. Schuster(Philadelphia University)Randall C. Walker(WinnMed)Kathleen WannemuehlerJohn R. Wingard(University of Florida)Tom ChillerPeter G. Pappas(University of Alabama at Birmingham)

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Abstract

In this national prospective surveillance study of IFIs in HSCT recipients, the cumulative incidence was highest for aspergillosis, followed by candidiasis. Understanding the epidemiologic trends and burden of IFIs may lead to improved management strategies and study design.

Antifungal resistance and susceptibility Fungal Infections and Studies Neutropenia and Cancer InfectionsMedicineAspergillosisCumulative incidenceZygomycosisIncidence (geometry)Hematopoietic stem cell transplantationTransplantationNeutropeniaEpidemiologyRetrospective cohort study