article Open AccessTop 10% cited
Use of induced sputum cell counts to investigate airway inflammation in asthma.
Thorax · 1992 · Vol. 47(1) · pp. 25–29
Isabelle Pin✉(St. Joseph's Hospital)Peter G. Gibson(St. Joseph's Hospital)R Kolendowicz(St. Joseph's Hospital)Adele Girgis-Gabardo(St. Joseph's Hospital)Judah A. Denburg(St. Joseph's Hospital)F.E. Hargreave(St. Joseph's Hospital)Jerry Dolovich(St. Joseph's Hospital)
Abstract
Induced sputum is capable of detecting differences in cell counts between normal and asthmatic subjects and merits further development as a potential means of assessing airway inflammation in asthma.
Asthma and respiratory diseasesInhalation and Respiratory Drug DeliveryNeonatal Respiratory Health ResearchMedicineHypertonic salineSputumEosinophilInhalationAsthmaEosinophil cationic proteinRespiratory tractSalbutamolRespiratory system
MeSH terms
AdolescentAdultAgedAsthmaBasophilsCell CountChildEosinophilsFemaleForced Expiratory VolumeHumansInflammationLungMaleMast Cells
Funding
- Canadian Lung Association
- Medical Research Council Canada
- Medical Research Council
Citations
920
FWCI
7.53
field-weighted impact
References
26
Percentile
98%
vs. same field & year
Citations per year
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Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations
Thorax · 2000 · 731 citations
References
Clinical biostatistics: LIV. The biostatistics of concordance
Clinical Pharmacology & Therapeutics · 1981 · 1,105 citations
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