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A Randomized Clinical Trial Evaluating Plasma Rich in Growth Factors (PRGF‐Endoret) Versus Hyaluronic Acid in the Short‐Term Treatment of Symptomatic Knee Osteoarthritis
Arthroscopy The Journal of Arthroscopic and Related Surgery · 2012 · Vol. 28(8) · pp. 1070–1078
Mikel Sánchez(Unidad de Cirugía Artroscópica)Nicolás Fiz(Unidad de Cirugía Artroscópica)Juan Azofra(Unidad de Cirugía Artroscópica)J Usabiaga(Biogipuzkoa Health Research Institute)Enmanuel Aduriz Recalde(Biogipuzkoa Health Research Institute)Antonio García Gutierrez(Biogipuzkoa Health Research Institute)Javier Albillos(Policlínica Gipuzkoa)Ramón Gárate(Policlínica Gipuzkoa)José Javier Aguirre(BTI Biotechnology Institute)Sabino Padilla(BTI Biotechnology Institute)Gorka Orive(BTI Biotechnology Institute)Eduardo Anitua✉(BTI Biotechnology Institute)
Abstract
Level I, randomized controlled multicenter trial.
Osteoarthritis Treatment and MechanismsPeriodontal Regeneration and TreatmentsKnee injuries and reconstruction techniquesOsteoarthritisMedicineRandomized controlled trialHyaluronic acidClinical trialAdverse effectRheumatologyConfidence intervalInternal medicinePhysical therapy
MeSH terms
Double-Blind MethodFemaleHumansHyaluronic AcidMaleMiddle AgedPlasmaTime FactorsArthralgiaOsteoarthritis, KneeIntercellular Signaling Peptides and Proteins
Citations
398
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22.47
field-weighted impact
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30
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100%
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References
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
Arthritis & Rheumatism · 1986 · 6,725 citations
The effects of specific medical conditions on the functional limitations of elders in the Framingham Study.
American Journal of Public Health · 1994 · 1,600 citations
Platelet‐Rich Plasma Intra‐Articular Injection Versus Hyaluronic Acid Viscosupplementation as Treatments for Cartilage Pathology: From Early Degeneration to Osteoarthritis
Arthroscopy The Journal of Arthroscopic and Related Surgery · 2011 · 576 citations
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