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A comparison between cystatin C, plasma creatinine and the Cockcroft and Gault formula for the estimation of glomerular filtration rate

Nephrology Dialysis Transplantation · 2003 · Vol. 18(10) · pp. 2024–2031

Franciscus J. Hoek✉(Academic Medical Center)

Abstract

Cys C shows a high correlation with GFR. With a very simple formula, cys C gives a good estimate of GFR, more accurate and precise than C&G. Because biological variation is low, cys C gives also a good assessment of GFR changes during follow-up. Cys C is the preferred endogenous parameter for GFR.

Chronic Kidney Disease and Diabetes Dialysis and Renal Disease Management Acute Kidney Injury ResearchRenal functionCystatin CCreatinineMedicineUrologyInternal medicineReceiver operating characteristicArea under the curveEndocrinologyPlasma clearance

MeSH terms

AdolescentAdultAgedChildCreatinineDiabetes Mellitus, Type 2Diabetic NephropathiesFemaleGlomerular Filtration RateHumansKidneyMaleMiddle AgedModels, BiologicalProbability

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