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Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Improves Survival of Patients with Peritoneal Carcinomatosis from Gastric Cancer: Final Results of a Phase III Randomized Clinical Trial
Annals of Surgical Oncology · 2011 · Vol. 18(6) · pp. 1575–1581
Xiaojun Yang✉(Wuhan University)Chaoqun Huang(Zhongnan Hospital of Wuhan University)Tao Suo(Zhongshan Hospital)Lie-Jun Mei(Wuhan University)Guoliang Yang(Wuhan University)Fulin Cheng(Wuhan University)Yunfeng Zhou(Zhongnan Hospital of Wuhan University)Bin Xiong(Zhongnan Hospital of Wuhan University)Yutaka YonemuraYan Li(Wuhan University)
Abstract
For synchronous gastric PC, CRS + HIPEC with mitomycin C 30 mg and cisplatin 120 mg may improve survival with acceptable morbidity.
Intraperitoneal and Appendiceal MalignanciesOvarian cancer diagnosis and treatmentNeuroendocrine Tumor Research AdvancesMedicineHyperthermic intraperitoneal chemotherapySurgical oncologyRandomized controlled trialSurgeryPeritoneal carcinomatosisConfidence intervalClinical endpointCancerAdverse effect
MeSH terms
AdenocarcinomaAdultAgedAntineoplastic Combined Chemotherapy ProtocolsAdenocarcinoma, MucinousCarcinoma, Squamous CellCisplatinCombined Modality TherapyFemaleHumansHyperthermia, InducedInjections, IntraperitonealMaleMiddle AgedNeoplasm Staging
Funding
- National Natural Science Foundation of China
- Science Fund for Creative Research Groups
Citations
679
FWCI
32.71
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References
28
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100%
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References
Morbidity and Mortality Analysis of 200 Treatments With Cytoreductive Surgery and Hyperthermic Intraoperative Intraperitoneal Chemotherapy Using the Coliseum Technique
Annals of Surgical Oncology · 1999 · 388 citations
Randomized Trial of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy Versus Systemic Chemotherapy and Palliative Surgery in Patients With Peritoneal Carcinomatosis of Colorectal Cancer
Journal of Clinical Oncology · 2003 · 2,010 citations
A Systematic Review and Meta-analysis of the Randomized Controlled Trials on Adjuvant Intraperitoneal Chemotherapy for Resectable Gastric Cancer
Annals of Surgical Oncology · 2007 · 349 citations
Peritoneal Carcinomatosis from Gastric Cancer: A Multi-Institutional Study of 159 Patients Treated by Cytoreductive Surgery Combined with Perioperative Intraperitoneal Chemotherapy
Annals of Surgical Oncology · 2010 · 484 citations
Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer
New England Journal of Medicine · 2006 · 6,297 citations
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