review Open AccessTop 1% cited
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
American Journal of Clinical Nutrition · 2011 · Vol. 93(4) · pp. 884S–890S
Pablo J. Fernández-Marcos(École Polytechnique Fédérale de Lausanne)Johan Auwerx✉
Adipose Tissue and MetabolismMitochondrial Function and PathologyPeroxisome Proliferator-Activated ReceptorsRegulatorMitochondrial biogenesisCoactivatorBiogenesisCell biologyPeroxisomePPARGC1AMaster regulatorTranscription factorMitochondrion
MeSH terms
AnimalsEnergy MetabolismGene Expression RegulationHumansMitochondriaProtein Processing, Post-TranslationalGene ExpressionPPAR gamma
Citations
1,196
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28.40
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References
The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes
Molecular and Cellular Biology · 2000 · 1,175 citations
Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
Developmental Cell · 2008 · 802 citations
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α
The EMBO Journal · 2007 · 1,271 citations
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
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