Integrin signalling at a glance

Abstract

Integrins are a major family of cell-surface-adhesion receptors that are expressed in all metazoans. They are heterodimers of noncovalently associated α and β subunits, each of which is a single-pass type I transmembrane protein ([Humphries et al., 2006][1]; [Hynes, 2002][2]). The specific binding