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The Prevention of Chronic Postsurgical Pain Using Gabapentin and Pregabalin

Anesthesia & Analgesia · 2012 · Vol. 115(2) · pp. 428–442
Hance ClarkeRobert P. BoninBeverley A. OrserMarina EnglesakisDuminda N. WijeysunderaJoel Katz

Abstract

The present review supports the view that perioperative administration of gabapentin and pregabalin are effective in reducing the incidence of CPSP. Better-designed and appropriately powered clinical trials are needed to confirm these early findings.

Anesthesia and Pain ManagementPain Management and Opioid UseNausea and vomiting managementPregabalinMedicineGabapentinPerioperativeAnalgesicChronic painClinical trialAnesthesiaMEDLINERandomization

MeSH terms

PregabalinGabapentinAdolescentAdultAgedAged, 80 and overAminesAnalgesicsCyclohexanecarboxylic AcidsDrug Administration ScheduleFemalegamma-Aminobutyric AcidHumansMaleMiddle Aged
Citations
478
FWCI
43.78
field-weighted impact
References
91
Percentile
100%
vs. same field & year
Citations per year
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