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Treatments of Negative Symptoms in Schizophrenia: Meta-Analysis of 168 Randomized Placebo-Controlled Trials
Schizophrenia Bulletin · 2014 · Vol. 41(4) · pp. 892–899
Paolo Fusar‐Poli(King's College London)Evangelos Papanastasiou✉(King's College London)Daniel Ståhl(King's College London)Matteo Rocchetti(University of Pavia)William T. Carpenter(University of Maryland, Baltimore)Sukhwinder S. Shergill(King's College London)Philip McGuire(King's College London)
Abstract
Although some statistically significant effects on negative symptoms were evident, none reached the threshold for clinically significant improvement.
Schizophrenia research and treatmentTreatment of Major DepressionMental Health Research TopicsPlaceboRandomized controlled trialMedicineSchizophrenia (object-oriented programming)Meta-analysisInternal medicineScale for the Assessment of Negative SymptomsClinical Global ImpressionBrief Psychiatric Rating ScalePsychological intervention
MeSH terms
HumansSchizophreniaRandomized Controlled Trials as TopicOutcome Assessment, Health Care
Funding
- South London and Maudsley NHS Foundation Trust
- National Alliance for Research on Schizophrenia and Depression
- National Institute for Health and Care Research
- King's College London
- Institute of Psychiatry, Psychology and Neuroscience, King’s College London
Citations
685
FWCI
24.57
field-weighted impact
References
68
Percentile
100%
vs. same field & year
Citations per year
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Schizophrenia Bulletin · 1987 · 21,169 citations
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