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A whole-genome assembly of the domestic cow, Bos taurus

Genome biology · 2009 · Vol. 10(4) · pp. R42–R42

Aleksey V. Zimin✉(University of Maryland, College Park)Arthur L. Delcher(University of Maryland, College Park)Liliana Florea(University of Maryland, College Park)David R. Kelley(University of Maryland, College Park)Michael C. Schatz(University of Maryland, College Park)Daniela Puiu(University of Maryland, College Park)Finnian Hanrahan(University of Maryland, College Park)Geo Pertea(University of Maryland, College Park)Curtis P. Van Tassell(Agricultural Research Service)Tad S. Sonstegard(Agricultural Research Service)Guillaume Marçais(University of Maryland, College Park)Michael Roberts(University of Maryland, College Park)Poorani Subramanian(University of Maryland, College Park)James A. Yorke(University of Maryland, College Park)Steven L. Salzberg(University of Maryland, College Park)

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Abstract

By using independent mapping data and conserved synteny between the cow and human genomes, we were able to construct an assembly with excellent large-scale contiguity in which a large majority (approximately 91%) of the genome has been placed onto the 30 B. taurus chromosomes. We constructed a new cow-human synteny map that expands upon previous maps. We also identified for the first time a portion of the B. taurus Y chromosome.

Genetic and phenotypic traits in livestock Animal Genetics and Reproduction Genetic Mapping and Diversity in Plants and AnimalsBiologyHuman geneticsGenomeGenome BiologyEvolutionary biologySequence assemblyGenomicsGeneticsComputational biologyGene