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In vitro antifungal evaluation and structure–activity relationships of a new series of chalcone derivatives and synthetic analogues, with inhibitory properties against polymers of the fungal cell wall

Bioorganic & Medicinal Chemistry · 2001 · Vol. 9(8) · pp. 1999–2013

Silvia N. López(National University of Rosario)María Victoria Castelli(National University of Rosario)Susana Zacchino✉(National University of Rosario)José N Domı́nguez(Central University of Venezuela)Gricela Lobo(Central University of Venezuela)Jaime Charris-Charris(Central University of Venezuela)Juan Carlos G. Cortés(Consejo Superior de Investigaciones Científicas)J. Ribas(Consejo Superior de Investigaciones Científicas)Cristina M. Devia(National University of San Luis)Ana M. Rodrı́guez(National University of San Luis)Ricardo D. Enriz(National University of San Luis)

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Fungal Plant Pathogen Control Plant-Microbe Interactions and Immunity Phytochemical compounds biological activitiesChalconeChemistryIn vitroSaccharomyces cerevisiaeChitin synthaseAntifungalEnzymeCell wallChalcone synthaseChitin

MeSH terms

Antifungal AgentsCell WallChalconeEvaluation Studies as TopicMicrobial Sensitivity TestsMolecular ConformationPolymersSaccharomyces cerevisiaeStructure-Activity Relationship