article Open AccessTop 10% cited
Predictors of Cognitive Decline and Mortality of Aged People Over a 10-Year Period
The Journals of Gerontology Series A · 2004 · Vol. 59(3) · pp. M268–M274
R. S. Tilvis✉(Helsinki University Hospital)Mervi Kahonen-VareJ. JolkkonenJaakko ValvanneKaisu PitkäläTimo Strandberg
Abstract
Long follow-up of a general aged population explains several inconsistencies of earlier reports. In 75+ individuals, general ill health is a strong associate of cognitive deficits. The strongest predictors of both cognitive decline and mortality are age, APOE4, manifest vascular diseases, and diabetes. The role of new potential predictors, feelings of loneliness and hypercalcemia, needs clinical testing.
Dementia and Cognitive Impairment ResearchBlood Pressure and Hypertension StudiesNutritional Studies and DietCognitive declineMedicineRelative riskPopulationDiabetes mellitusDementiaLonelinessInternal medicineStroke (engine)Atrial fibrillation
MeSH terms
AgedAged, 80 and overCognition DisordersFemaleFollow-Up StudiesGeriatricsHumansMaleMortalityPrognosisProspective StudiesTime Factors
Funding
- Helsingin Yliopisto
- Academy of Finland
Citations
574
FWCI
7.90
field-weighted impact
References
40
Percentile
98%
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Citations per year
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References
Association of diabetes mellitus and dementia: The Rotterdam Study
Diabetologia · 1996 · 674 citations
Diabetes mellitus and the risk of dementia
Neurology · 1999 · 2,113 citations
A New Clinical Scale for the Staging of Dementia
The British Journal of Psychiatry · 1982 · 7,000 citations
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