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Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host

BMC Genomics · 2008 · Vol. 9(1) · pp. 1–1

Zhiyong Xi✉(University of Kentucky)Laurent Gavotte(University of Kentucky)Yan Xie(University of Kentucky)Stephen L. Dobson(University of Kentucky)

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Abstract

Wolbachia infection is shown to affect the expression of multiple host genes, including Ance. Evidence for potential Ance involvement in the CI mechanism is described, including the prior report of Ance in spermatid differentiation, Wolbachia-induced sex-specific effects on Ance expression and an Ance mutation effect on CI levels. The results support the use of Wolbachia infected cell cultures as an appropriate model for predicting in vivo host/Wolbachia interactions.

Insect symbiosis and bacterial influences Invertebrate Immune Response Mechanisms Insect-Plant Interactions and ControlWolbachiaBiologyCytoplasmic incompatibilityObligateGeneticsDrosophila melanogasterParthenogenesisGeneHost (biology)Intracellular parasite

MeSH terms

AnimalsCell LineDrosophilaFemaleGonadsHeat-Shock ProteinsPeptidyl-Dipeptidase AMalePhenotypeReproductionSex CharacteristicsSymbiosisDown-RegulationUp-RegulationGram-Negative Bacterial Infections