articleTop 1% cited
Gold Nanocages as Photothermal Transducers for Cancer Treatment
Small · 2010 · Vol. 6(7) · pp. 811–817
Jingyi Chen✉(Washington University in St. Louis)Charles Glaus(Washington University in St. Louis)Richard Laforest(Washington University in St. Louis)Qiang Zhang(Washington University in St. Louis)Yang Miao-xian(Washington University in St. Louis)Michael Gidding(Washington University in St. Louis)Michael J. Welch✉(Washington University in St. Louis)Younan Xia✉(Washington University in St. Louis)
Abstract
Gold nanocages represent a new class of nanomaterials with compact size and tunable optical properties in the near-infrared region. They passively accumulate in the tumor after intravenous injection. By exposing tumors to a near-infrared diode laser, the photothermal effect of the Au nanocages selectively destroys tumor tissue with minimum damage to the surrounding healthy tissue.
Nanoplatforms for cancer theranosticsGold and Silver Nanoparticles Synthesis and ApplicationsPhotoacoustic and Ultrasonic ImagingNanocagesPhotothermal therapyMaterials sciencePhotothermal effectNanomaterialsNanotechnologyLaserDiodeInfraredOptoelectronics
MeSH terms
AnimalsGoldHumansInjections, IntravenousLightNeoplasmsPolyethylene GlycolsSpectrophotometry, UltravioletTemperatureTissue DistributionTomography, X-Ray ComputedTransducersSpectroscopy, Near-InfraredFluorodeoxyglucose F18Xenograft Model Antitumor Assays
Citations
690
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35.95
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References
35
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100%
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References
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Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods
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Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles
Cancer Letters · 2004 · 1,804 citations
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Chemical Physics Letters · 1998 · 2,242 citations
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