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High plasma phosphate as a risk factor for decline in renal function and mortality in pre-dialysis patients

Nephrology Dialysis Transplantation · 2007 · Vol. 22(10) · pp. 2909–2916

Nora Voormolen✉(Academic Medical Center)Marlies Noordzij(Groene Hart Ziekenhuis)Diana C. Grootendorst(Spaarne Gasthuis)Ivo Beetz(Spaarne Gasthuis)Y W J Sijpkens(Máxima Medisch Centrum)Jeannette G. van Manen(Leiden University Medical Center)E. W. Boeschoten(Spaarne Gasthuis)R. M. Huisman(Rijnland Ziekenhuis)Raymond T. Krediet(Spaarne Gasthuis)Friedo W. Dekker(Deventer Ziekenhuis)the PREPARE study group

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Abstract

High plasma phosphate is an independent risk factor for a more rapid decline in renal function and a higher mortality during the pre-dialysis phase. Plasma phosphate within the normal range is likely of vital importance in pre-dialysis patients.

Parathyroid Disorders and Treatments Dialysis and Renal Disease Management Neurological and metabolic disordersMedicineRenal functionDialysisKidney diseaseInternal medicineUrologyPhosphate binderPhosphateHemodialysisRisk factor

MeSH terms

AgedAlgorithmsFemaleGlomerular Filtration RateRenal DialysisHumansKidneyKidney Failure, ChronicMaleMiddle AgedPhosphatesRegression AnalysisRisk FactorsTreatment OutcomeHyperphosphatemia