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Alcohol Drinking in Never Users of Tobacco, Cigarette Smoking in Never Drinkers, and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium

JNCI Journal of the National Cancer Institute · 2007 · Vol. 99(10) · pp. 777–789

M. Hashibe✉(Centre International de Recherche sur le Cancer)Paul E. Brennan(Centre International de Recherche sur le Cancer)Simone Benhamou(Inserm)Xavier Castellsagué(Institut Català d'Oncologia)Chen X. Chen(Fred Hutch Cancer Center)María Paula Curado(Fred Hutch Cancer Center)Luigino Dal Maso(Hospital Araújo Jorge)Alexander W. Daudt(Centro di Riferimento Oncologico)Eleonóra Fabiánová(Universidade Federal do Rio Grande do Sul)V. Wunsch-Filho(Children's Specialized Hospital)Silvia Franceschi(Centre International de Recherche sur le Cancer)Richard B. Hayes(National Institutes of Health)R. HerreroSérgio Koifman(Fundação Oswaldo Cruz)Carlo La Vecchia(University of Milan)P. Lazarus(Pennsylvania State University)Fabio Levi(University of Lausanne)Dana MateșE. Matos(University of Buenos Aires)Ana B Menezes(Universidade Federal de Pelotas)Joshua Muscat(University of Milan)José Eluf‐Neto(Universidade de São Paulo)A.F. OlshanP. Rudnai(Agricultural Biotechnology Institute)Stephen M. Schwartz(Fred Hutch Cancer Center)E. SmithErich M. Sturgis(The University of Texas MD Anderson Cancer Center)Neonila Szeszenia‐Dąbrowska(Nofer Institute of Occupational Medicine)R. Talamini(Centro di Riferimento Oncologico)Qi Wei(The University of Texas MD Anderson Cancer Center)D. M. Winn(National Institutes of Health)Давид Заридзе(Russian Cancer Research Center NN Blokhin)Witold ZatońskiZuo‐Feng Zhang(University of California, Los Angeles)J. Berthiller(Centre International de Recherche sur le Cancer)P. Boffetta(Centre International de Recherche sur le Cancer)

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Abstract

Our results represent the most precise estimates available of the independent association of each of the two main risk factors of head and neck cancer, and they exemplify the strengths of large-scale consortia in cancer epidemiology.

Head and Neck Cancer Studies Cancer-related molecular mechanisms researchMedicineOdds ratioHead and neck cancerConfidence intervalLogistic regressionCancerEpidemiologyRisk factorCase-control studyEnvironmental health