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On the Hydrazinolysis of Proteins and Peptides: A Method for the Characterization of Carboxyl-terminal Amino Acids in Proteins
Bulletin of the Chemical Society of Japan · 1952 · Vol. 25(3) · pp. 214–218
Abstract
Abstract (1) A brief method for the characterization of carboxyl-terminal amino acids in peptides and proteins was investigated. (2) Several new amino acid hydrazides were synthesized. (3) Soveral di- and tri-peptides were hydrazinolyzed and identified their carboxylterminal amino acid. (4) The method was applied to beef insulin and tyrocidin for the demonstration of its applicability.
Protein Structure and DynamicsEnzyme Catalysis and ImmobilizationChemistryAmino acidTerminal (telecommunication)Characterization (materials science)BiochemistryAmino acid residuePeptide sequenceCombinatorial chemistryNanotechnology
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