article Open AccessTop 10% cited
Identification of chemically diverse Chk1 inhibitors by receptor-based virtual screening
Bioorganic & Medicinal Chemistry · 2006 · Vol. 14(14) · pp. 4792–4802
Nicolas Foloppe✉(Granta Design (United Kingdom))Lisa M. Fisher(Granta Design (United Kingdom))Rob Howes(Granta Design (United Kingdom))Andrew Potter(Granta Design (United Kingdom))Alan Robertson(Granta Design (United Kingdom))A.E. Surgenor(Granta Design (United Kingdom))
Enzyme Structure and FunctionDNA Repair MechanismsComputational Drug Discovery MethodsChemistryVirtual screeningDocking (animal)Binding siteComputational biologySmall moleculeContext (archaeology)KinaseDrug discoveryChemical biology
MeSH terms
Checkpoint Kinase 1Adenosine TriphosphateBinding SitesBinding, CompetitiveDrug Evaluation, PreclinicalHumansLigandsModels, MolecularProtein KinasesUser-Computer InterfaceMolecular StructureCrystallography, X-RayProtein Kinase InhibitorsIn Vitro Techniques
Citations
362
FWCI
4.23
field-weighted impact
References
68
Percentile
95%
vs. same field & year
Citations per year
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References
Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation
Journal of Molecular Biology · 1995 · 1,535 citations
Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy
Journal of Medicinal Chemistry · 2004 · 9,717 citations
Docking and scoring in virtual screening for drug discovery: methods and applications
Nature Reviews Drug Discovery · 2004 · 3,899 citations
All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins
The Journal of Physical Chemistry B · 1998 · 14,418 citations
Predicting modes of toxic action from chemical structure: Acute toxicity in the fathead minnow (<i>Pimephales promelas</i>)
Environmental Toxicology and Chemistry · 1997 · 559 citations
Evaluation of the FLEXX incremental construction algorithm for protein-ligand docking
Proteins Structure Function and Bioinformatics · 1999 · 894 citations
The Protein Data Bank
Nucleic Acids Research · 2000 · 39,191 citations
Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94
Journal of Computational Chemistry · 1996 · 5,215 citations
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