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Ethanol Directly Excites Dopaminergic Ventral Tegmental Area Reward Neurons

Alcoholism Clinical and Experimental Research · 1999 · Vol. 23(11) · pp. 1848–1852
Mark S. BrodieChristine PesoldSarah B. Appel

Abstract

These data provide strong evidence that ethanol directly excites dopaminergic VTA neurons, as this excitation still occurs in the absence of input from surrounding neurons.

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology ResearchReceptor Mechanisms and SignalingVentral tegmental areaDopaminergicDopamineNeuroscienceNucleus accumbensTyrosine hydroxylaseChemistryElectrophysiologyMesolimbic pathwayGABAergic

MeSH terms

Action PotentialsEthanolAnimalsAnimals, NewbornCentral Nervous System DepressantsDopamineNeuronsRats, Inbred F344RewardVentral Tegmental AreaRats
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