articleTop 10% cited

Preoperative irradiation affects functional results after surgery for rectal cancer

Diseases of the Colon & Rectum · 1998 · Vol. 41(5) · pp. 543–549

Michael Dahlberg✉(Uppsala University Hospital)Bengt Glimelius(Uppsala University Hospital)Wilhelm Graf(Uppsala University Hospital)Lars Påhlman(Uppsala University Hospital)

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Abstract

The study indicates that high-dose radiotherapy influences long-term bowel function, thus emphasizing the need for finding predictive factors for local recurrence to exclude patients with a very high probability for cure with surgery alone and to use optimized radiation techniques.

Colorectal Cancer Surgical Treatments Colorectal and Anal Carcinomas Anorectal Disease Treatments and OutcomesMedicineRadiation therapyColorectal cancerColorectal surgerySurgeryCancerSurgical oncologyBowel functionRectumAnorectal manometry

MeSH terms

AdultAgedAged, 80 and overAnastomosis, SurgicalFemaleHumansMaleMiddle AgedPreoperative CareProspective StudiesRectal NeoplasmsRectumTreatment OutcomeRadiotherapy, Adjuvant

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464

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T-Level Downstaging and Complete Pathologic Response After Preoperative Chemoradiation for Advanced Rectal Cancer Result in Decreased Recurrence and Improved Disease-Free Survival