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Histological and Ultrastructural Evaluation of the Effects of a Radiofrequency-Based Nonablative Dermal Remodeling Device

Archives of Dermatology · 2004 · Vol. 140(2) · pp. 204–9

Brian D. Zelickson✉(University of Minnesota)David A. Kist(University of Minnesota)Eric F. BernsteinDouglas B. Brown(Charles River Laboratories (Netherlands))Sergey M. Ksenzenko(Charles River Laboratories (Netherlands))Jay A. Burns(The University of Texas Southwestern Medical Center)Suzanne L. KilmerDavid A. MehreganKarl Pope

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Abstract

Our findings suggest that collagen fibril contraction occurs immediately after treatment and gives rise to tissue contraction and thermally mediated wounding, which induces new collagen production.

Dermatologic Treatments and Research Laser Applications in Dentistry and Medicine Skin Protection and AgingMedicineUltrastructureContraction (grammar)FibrilGround substancePathologyCollagen fibrilDermisWestern blotTendon

MeSH terms

AnimalsCattleCollagenDose-Response Relationship, RadiationFemaleHumansPilot ProjectsRadio WavesRadiographySkinTendonsAbdominal WallIn Vitro Techniques

Citations

373

FWCI

26.83

field-weighted impact

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100%

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Cited by

Photoaging: Mechanisms and repair

Journal of the American Academy of Dermatology · 2006 · 594 citations

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