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Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents

Bioorganic & Medicinal Chemistry · 2009 · Vol. 17(6) · pp. 2623–2631
Guang LiangLili ShaoYi WangChengguang ZhaoYanhui ChuJian XiaoYu ZhaoXiaokun LiShulin Yang
Curcumin's Biomedical ApplicationsNatural product bioactivities and synthesisPharmacological Effects of Medicinal PlantsCurcuminChemistryIn vivoPharmacokineticsIn vitroMoietyMetabolic stabilityPharmacologyLinkerMTT assay

MeSH terms

Antineoplastic AgentsCurcuminDrug Screening Assays, AntitumorHumansStructure-Activity RelationshipMolecular StructureCell Line, Tumor
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Cited by
The Essential Medicinal Chemistry of Curcumin
Journal of Medicinal Chemistry · 2017 · 1,824 citations
References
Anti-oxidant activities of curcumin and related enones
Bioorganic & Medicinal Chemistry · 2005 · 288 citations
Stability of curcumin in buffer solutions and characterization of its degradation products
Journal of Pharmaceutical and Biomedical Analysis · 1997 · 1,674 citations
Potential anticancer activity of turmeric (Curcuma longa)
Cancer Letters · 1985 · 678 citations
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Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents · Scinovex