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Changes in neuronal activation patterns in response to androgen deprivation therapy: a pilot study

BMC Cancer · 2010 · Vol. 10(1) · pp. 1–1
Monique M. CherrierPaul R. BorghesaniAmy L. SheltonCelestia S. Higano

Abstract

Findings, while preliminary, suggest that ADT reduces task-related neural activation in brain regions that are involved in mental rotation and accurate recall of spatial information.

Memory and Neural MechanismsSpatial Cognition and NavigationCancer-related cognitive impairment studiesFunctional magnetic resonance imagingAndrogen deprivation therapyMedicineNeuroimagingMagnetic resonance imagingRecallProstate cancerOncologyMental rotationInternal medicine

MeSH terms

AgedAndrogen AntagonistsAndrogensBrainCognitionHumansMagnetic Resonance ImagingMaleMiddle AgedNeuronsPilot ProjectsProstatic NeoplasmsQuality of LifeMental RecallSpace Perception

Funding

  • U.S. Department of Defense
  • U.S. Department of Veterans Affairs
  • National Institutes of Health
  • National Institute on Aging
  • National Center for Research Resources
  • DOD Prostate Cancer Research Program
Citations
396
FWCI
11.30
field-weighted impact
References
53
Percentile
99%
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Cited by
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Advanced Drug Delivery Reviews · 2011 · 1,621 citations
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