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Soil-Transmitted Helminth Reinfection after Drug Treatment: A Systematic Review and Meta-Analysis

PLoS neglected tropical diseases · 2012 · Vol. 6(5) · pp. e1621–e1621
Tie-Wu JiaSara E. MelvilleJürg UtzingerCharles H. KingXiao‐Nong Zhou

Abstract

STH reinfections occur rapidly after treatment, particularly for A. lumbricoides and T. trichiura. Hence, there is a need for frequent anthelmintic drug administrations to maximize the benefit of preventive chemotherapy. Integrated control approaches emphasizing health education and environmental sanitation are needed to interrupt transmission of STH.

Parasites and Host InteractionsHelminth infection and controlParasite Biology and Host InteractionsMedicineTrichuris trichiuraAscaris lumbricoidesInternal medicineMeta-analysisConfidence intervalHookworm InfectionsDewormingImmunologyHelminths

MeSH terms

AnimalsAnthelminticsAscariasisDrug TherapyHelminthiasisHookworm InfectionsHumansRecurrenceTrichuriasis

Funding

  • National Science Foundation
  • University of Cambridge
  • Chinese Center for Disease Control and Prevention
  • National Institutes of Health
Citations
435
FWCI
15.72
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References
100
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100%
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