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The impact of non‐motor symptoms on health‐related quality of life of patients with Parkinson's disease

Movement Disorders · 2011 · Vol. 26(3) · pp. 399–406

Pablo Martínez‐Martín✉(Biomedical Research Networking Center on Neurodegenerative Diseases)Carmen Rodríguez‐Blázquez(Biomedical Research Networking Center on Neurodegenerative Diseases)Mónica Kurtis(Hospital Ruber Internacional)К. Ray Chaudhuri(University Hospital Lewisham)on Behalf of the NMSS Validation Group

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Abstract

To our knowledge, this is the first study to determine in a holistic manner the impact of the non-motor symptoms on HRQoL of Parkinson's disease patients. The results show that non-motor symptoms have, as a whole, a greater impact on HRQoL than motor symptoms and non-motor symptoms progression contributes importantly to HRQoL decline in patients with Parkinson's disease.

Parkinson's Disease Mechanisms and Treatments Botulinum Toxin and Related Neurological Disorders Restless Legs Syndrome ResearchParkinson's diseaseQuality of life (healthcare)NocturiaMedicineMotor symptomsPhysical therapyDiseaseCross-sectional studyInternal medicine

MeSH terms

AgedCross-Sectional StudiesDisability EvaluationFemaleGastrointestinal DiseasesHealth StatusHumansInternational CooperationMaleMiddle AgedParkinson DiseasePsychometricsQuality of LifeRespiratory Tract DiseasesSeverity of Illness Index

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