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Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases

Bioorganic & Medicinal Chemistry · 2006 · Vol. 14(11) · pp. 3758–3765
Sham M. SondhiNirupma SinghAshok KumarOlivier LozachLaurent Meijer
Synthesis and biological activityBioactive Compounds and Antitumor AgentsSynthesis and Biological EvaluationChemistryBenzoxazoleBenzimidazoleCyclin-dependent kinaseAnalgesicStereochemistryPharmacologyOrganic chemistryBiochemistry

MeSH terms

AnalgesicsAnimalsAnti-Inflammatory Agents, Non-SteroidalBenzimidazolesBenzoxazolesDrug Evaluation, PreclinicalEnzyme ActivationFemaleProtein KinasesSchiff BasesStructure-Activity RelationshipCDC2 Protein KinaseRats, WistarGlycogen Synthase Kinase 3Cyclin-Dependent Kinase 5
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Cited by
The therapeutic journey of benzimidazoles: A review
Bioorganic & Medicinal Chemistry · 2012 · 787 citations
References
Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs
Experimental Biology and Medicine · 1962 · 5,635 citations
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