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Efficacy of omeprazole in functional dyspepsia: double‐blind, randomized, placebo‐controlled trials (the Bond and Opera studies)

Alimentary Pharmacology & Therapeutics · 1998 · Vol. 12(11) · pp. 1055–1065

Talley✉(Nepean Hospital)Meineche‐Schmidt(University of Sydney)Paré(Nepean Hospital)D DUCKWORTH(Nepean Hospital)Räisänen(Nepean Hospital)Pap(University of Sydney)Kordecki(University of Sydney)Schmid(Nepean Hospital)

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Abstract

Omeprazole is modestly superior to placebo in functional dyspepsia at standard (20 mg) and low doses (10 mg) but not in patients with dysmotility-like dyspepsia.

Helicobacter pylori-related gastroenterology studies Gastrointestinal motility and disorders Gastroesophageal reflux and treatmentsOmeprazoleMedicinePlaceboDouble blindRandomized controlled trialPlacebo-controlled studyInternal medicineGastroenterologyAlternative medicinePathology

MeSH terms

Adenosine TriphosphatasesAdultAnti-Ulcer AgentsDouble-Blind MethodDyspepsiaFemaleHumansMaleOmeprazoleQuality of LifeConfidence IntervalsChi-Square DistributionHelicobacter Infections

Citations

388

FWCI

24.82

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Current concepts in the management of <i>Helicobacter pylori</i> infection—The Maastricht 2‐2000 Consensus Report