article Open AccessTop 10% cited
Corticosteroid Pharmacokinetics in the Inner Ear Fluids: An Animal Study Followed by Clinical Application
The Laryngoscope · 1999 · Vol. 109(S91) · pp. 1–17
Lorne S. Parnes✉(Western University)Aihua Sun(Western University)David J. Freeman(Western University)
Abstract
Overall injection of intratympanic corticosteroids for the treatment of hearing loss in inner ear disorders appears to be both safe and highly effective for certain disorders. The concept of this technique is supported by animal experimental data. The findings from the present study warrant further clinical application and experimental investigation.
Vestibular and auditory disordersHearing, Cochlea, Tinnitus, GeneticsEar Surgery and Otitis MediaMedicinePharmacokineticsMethylprednisoloneInner earDexamethasoneCorticosteroidHearing lossOtotoxicityPerilymphOtitis
MeSH terms
Administration, OralAdultAgedAnimalsAnti-Inflammatory AgentsAutoimmune DiseasesChromatography, High Pressure LiquidDexamethasoneEar, MiddleFemaleGlucocorticoidsGuinea PigsHearing Loss, SensorineuralHumansHydrocortisone
Citations
630
FWCI
7.47
field-weighted impact
References
48
Percentile
97%
vs. same field & year
Citations per year
References
The Efficacy of Steroids in the Treatment of Idiopathic Sudden Hearing Loss: A Double-blind Clinical Study
Archives of Otolaryngology - Head and Neck Surgery · 1980 · 927 citations
Sudden hearing loss: Eight years' experience and suggested prognostic table
The Laryngoscope · 1984 · 885 citations
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