articleTop 10% cited

Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans

Neurology · 2001 · Vol. 57(10) · pp. 1899–1901

Michael A. Nitsche✉(University of Göttingen)Walter Paulus(University of Göttingen)

Abstract

The authors show that in the human transcranial direct current stimulation is able to induce sustained cortical excitability elevations. As revealed by transcranial magnetic stimulation, motor cortical excitability increased approximately 150% above baseline for up to 90 minutes after the end of stimulation. The feasibility of inducing long-lasting excitability modulations in a noninvasive, painless, and reversible way makes this technique a potentially valuable tool in neuroplasticity modulation.

Transcranial Magnetic Stimulation Studies EEG and Brain-Computer Interfaces Neuroscience and Neural EngineeringTranscranial magnetic stimulationNeuroscienceStimulationMotor cortexTranscranial direct-current stimulationNeuroplasticityTranscranial alternating current stimulationBrain stimulationMedicinePsychology

MeSH terms

Brain MappingDominance, CerebralElectroencephalographyElectric Stimulation TherapyHumansMotor CortexSynaptic TransmissionSignal Processing, Computer-AssistedMuscle, SkeletalEvoked Potentials, Motor

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Safety criteria for transcranial direct current stimulation (tDCS) in humans