review Open AccessTop 1% cited
FTY720: Sphingosine 1-Phosphate Receptor-1 in the Control of Lymphocyte Egress and Endothelial Barrier Function
American Journal of Transplantation · 2004 · Vol. 4(7) · pp. 1019–1025
Volker Brinkmann✉(Novartis (Switzerland))Jason G. Cyster(Howard Hughes Medical Institute)Timothy Hla(UConn Health)
Sphingolipid Metabolism and SignalingAdenosine and Purinergic SignalingRenal Diseases and GlomerulopathiesSphingosine-1-phosphateS1PR1Cell biologyMedicineSphingosineImmunologyReceptorSphingosine-1-phosphate receptorLymphocyte homing receptorEndothelium
MeSH terms
Fingolimod HydrochlorideAnimalsClinical Trials as TopicEndothelium, VascularHeart RateHumansImmunosuppressive AgentsInflammationLymphocytesLysophospholipidsModels, BiologicalModels, ChemicalPhosphorylationPropylene GlycolsProtein Binding
Citations
474
FWCI
13.69
field-weighted impact
References
63
Percentile
99%
vs. same field & year
Citations per year
References
Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720
Bioorganic & Medicinal Chemistry Letters · 1995 · 308 citations
Cytoskeletal regulation of pulmonary vascular permeability
Journal of Applied Physiology · 2001 · 990 citations
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