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Midlife and Late-Life Obesity and the Risk of Dementia
Archives of Neurology · 2009 · Vol. 66(3) · pp. 336–42
Annette L. Fitzpatrick✉(The Coordinating Center)Lewis H. Kuller(University of Pittsburgh)Oscar L. López(University of Pittsburgh)Paula Diehr(University of Washington)Ellen S. O’Meara(University of Washington)W.T. Longstreth(University of Washington)José A. Luchsinger(Columbia University)
Abstract
These results help explain the "obesity paradox" as differences in dementia risk across time are consistent with physical changes in the trajectory toward disability.
Nutrition and Health in AgingNutritional Studies and DietFrailty in Older AdultsDementiaMedicineOverweightBody mass indexHazard ratioUnderweightVascular dementiaObesityGerontologyProspective cohort study
MeSH terms
AgedAged, 80 and overAgingAlzheimer DiseaseAnthropometryEvaluation Studies as TopicFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedObesityProspective StudiesRisk
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