article Open AccessTop 1% cited
Mechanisms of C–H bond activation: rich synergy between computation and experiment
Dalton Transactions · 2009 · pp. 5820–5820
Y. Boutadla(University of Leicester)David L. Davies✉(University of Leicester)Stuart A. Macgregor✉(Heriot-Watt University)Amalia I. Poblador‐Bahamonde(Heriot-Watt University)
Abstract
Recent computational studies of C-H bond activation at late transition metal systems are discussed and processes where lone pair assistance via heteroatom co-ligands or carboxylates are highlighted as a particularly promising means of cleaving C-H bonds. The term 'ambiphilic metal ligand activation' (AMLA) is introduced to describe such reactions.
Catalytic C–H Functionalization MethodsAsymmetric Hydrogenation and CatalysisSynthesis and Catalytic ReactionsHeteroatomLigand (biochemistry)ChemistryLone pairBondMetalStereochemistryTransition metalMoleculeCatalysis
Funding
- Royal Society
- Engineering and Physical Sciences Research Council
Citations
438
FWCI
18.62
field-weighted impact
References
106
Percentile
100%
vs. same field & year
Citations per year
Cited by
Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations
Accounts of Chemical Research · 2013 · 1,623 citations
Recent development of direct asymmetric functionalization of inert C–H bonds
RSC Advances · 2013 · 574 citations
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
Chemical Reviews · 2011 · 3,829 citations
Functionalization of Organic Molecules by Transition‐Metal‐Catalyzed C(sp<sup>3</sup>)H Activation
Chemistry - A European Journal · 2010 · 1,074 citations
References
Aromatic substitution of styrene-palladium chloride complex
Tetrahedron Letters · 1967 · 588 citations
Metal−Ligand Bifunctional Catalysis: A Nonclassical Mechanism for Asymmetric Hydrogen Transfer between Alcohols and Carbonyl Compounds
The Journal of Organic Chemistry · 2001 · 857 citations
Organometallic alkane CH activation
Journal of Organometallic Chemistry · 2004 · 472 citations
Bifunctional transition metal-based molecular catalysts for asymmetric syntheses
Organic & Biomolecular Chemistry · 2005 · 636 citations
Transition metal catalyzed oxidative functionalization of carbon–hydrogen bonds
Tetrahedron · 2006 · 883 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.