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Chikungunya Virus-associated Long-term Arthralgia: A 36-month Prospective Longitudinal Study
PLoS neglected tropical diseases · 2013 · Vol. 7(3) · pp. e2137–e2137
Clémentine Schilte(Institut Pasteur)Frédérik Staikovsky(Centre Hospitalier Universitaire de La Réunion)Thérèse Couderc(Institut Pasteur)Yoann Madec(Institut Pasteur)Florence Carpentier(Biologie et Gestion des Risques en Agriculture)Somar Kassab(Centre Hospitalier Universitaire de La Réunion)Matthew L. Albert(Sorbonne Paris Cité)Marc Lecuit✉(Délégation Paris 5)Alain Michault✉(Centre Hospitalier Universitaire de La Réunion)
Abstract
This study demonstrates that chronic arthralgia is a frequent complication of acute Chikungunya disease and suggests that it results from a local rather than systemic inflammation.
Mosquito-borne diseases and controlViral Infections and VectorsAutoimmune and Inflammatory Disorders ResearchChikungunyaMedicineCohortProspective cohort studyArthritisCohort studyOutbreakReactive arthritismyalgiaImmunology
MeSH terms
AdultAgedAged, 80 and overDisease OutbreaksFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesRisk FactorsCohort StudiesReunionAlphavirus InfectionsArthralgia
Funding
- Institut National de la Santé et de la Recherche Médicale
Citations
481
FWCI
31.64
field-weighted impact
References
44
Percentile
100%
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Citations per year
References
A Mouse Model for Chikungunya: Young Age and Inefficient Type-I Interferon Signaling Are Risk Factors for Severe Disease
PLoS Pathogens · 2008 · 598 citations
Post-Epidemic Chikungunya Disease on Reunion Island: Course of Rheumatic Manifestations and Associated Factors over a 15-Month Period
PLoS neglected tropical diseases · 2009 · 405 citations
Characterization of Reemerging Chikungunya Virus
PLoS Pathogens · 2007 · 489 citations
Genome Microevolution of Chikungunya Viruses Causing the Indian Ocean Outbreak
PLoS Medicine · 2006 · 1,177 citations
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