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Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer’s, Parkinson’s, and other neurodegenerative diseases

Bioorganic & Medicinal Chemistry · 2004 · Vol. 13(3) · pp. 773–783
Hailin ZhengLev WeinerOrit Bar‐AmSilvina EpsztejnZ. Ioav CabantchikAbraham WarshawskyMoussa B. H. YoudimMati Fridkin
Free Radicals and AntioxidantsMetal complexes synthesis and propertiesElectrochemical Analysis and ApplicationsChemistryNeuroprotectionChelationAntioxidantDeferiproneMoietyBifunctionalNeurotoxicityHydroxyl radicalBiochemistry

MeSH terms

Alzheimer DiseaseAntioxidantsCell LineCell Membrane PermeabilityElectron Spin Resonance SpectroscopyHumansIron Chelating AgentsMonoamine Oxidase InhibitorsMagnetic Resonance SpectroscopyParkinson DiseaseMass SpectrometryFree Radical ScavengersNeuroprotective AgentsNeurodegenerative DiseasesK562 Cells
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