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Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

Neurobiology of Aging · 2008 · Vol. 30(10) · pp. 1574–1586
Susanne HauptmannIsabel ScherpingStephan DröseUlrich BrandtKathrin SchulzMarina JendrachKristina LeunerAnne EckertWernér E.G. Müller
Alzheimer's disease research and treatmentsTryptophan and brain disordersPrion Diseases and Protein MisfoldingGenetically modified mouseMitochondrionExtracellularHyperphosphorylationTransgeneInternal medicineBiologyIntracellularEndocrinologyReactive oxygen species

MeSH terms

Adenosine TriphosphateAgingAlzheimer DiseaseAnimalsBrainDisease Models, AnimalElectron TransportFemaleHumansMice, Inbred C57BLMice, TransgenicMitochondriaReceptors, Cell SurfaceAmyloid beta-PeptidesAmyloid beta-Protein Precursor
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Alzheimer’s disease and its treatment by different approaches: A review
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References
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Journal of Biological Chemistry · 1951 · 317,666 citations
Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2004 · 458 citations
The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity
Journal of Immunological Methods · 1993 · 911 citations
Blue native PAGE
Nature Protocols · 2006 · 1,704 citations
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